Latest Research and News

Mendelian Code for Complex Disease

Mendelian Code for Complex Disease

GGSB MD-Ph.D. graduate student, David Blair, co- authored a study using over 100 million patient records to identify a nondegenerate code of deleterious variants in Mendelian loci that contributes to complex disease risk. The results were published in the September 26, 2013 issue of Cell.


National Centers for Systems biology program marks its 10th anniversary

The NIGMS National Centers for Systems Biology (NCSB) program enables cutting-edge systems biology research, training, education and outreach.To mark the program’s 10-year anniversary, NIGMS is hosting a special centers meeting (NIH, July 10-12th) that will highlight the program’s achievements.

Read more about the NIGSM systems biology program and the 15 national Centers

2013 Summer REU Students

CCSB welcomes the 2013 summer REU students

The 10-week Chicago Center for Systems Biology REU program kicked off this past Tuesday. Students will work in the labs of Kevin White, Michael Rust, Richard Carthew, Rick Morimoto and Ilya Ruvinsky, on projects ranging from circadian rhythms in cyanobacteria to Drosophila development.

Learn more about the CCSB summer program

Rick Morimoto

An organismal stress-sensing surveillance system

Center Fellow Patricija van Oosten-Hawle, Rick Morimoto and colleagues find that protein-folding stress that occurs in one tissue impacts the proteostasis capacity of other tissues. Their work reveals the existence of a transcellular chaperone signaling response that integrates cell-specific and organismal responses to maintain organismal proteostasis in response to localized stress.

Read the Northwestern University press release

Ilya Ruvinsky

Center Investigator recognized for excellence in graduate teaching

The CCSB congratulates Ilya Ruvinsky, recipient of the University of Chicago’s 2013 Faculty Award for Excellence in Graduate Teaching and Mentoring.

Ilya discusses teaching experiences and approaches in an interview with Megan Doherty.

Ravi Allada

Translation and timekeeping

Center investigator Ravi Allada’s group finds that ATAXIN-2, an RNA-associated protein involved in neurodegenerative disease, is a translational activator of the rate-limiting clock component PERIOD. Their findings highlight the importance of mechanisms of translation regulation on the function of the circadian clock.

The paper by Lim and Allada was published in Science.


Research Experiences for Undergraduates in 2014

2014 Systems Biology Research Experiences for Undergraduates (REU)

2014 Systems Biology Research Experiences for Undergraduates (REU)
Starts June 9, 2014

2014 Conte Center Research Experiences for Undergraduates (REU)

2014 Conte Center Research Experiences for Undergraduates (REU)
Starts June 16, 2014